Ykl-40 Glioblastoma

Autocrine Endothelin-3/Endothelin Receptor B Signaling ...
Autocrine Endothelin-3/Endothelin Receptor B Signaling Maintains Cellular and Molecular Properties of Glioblastoma Stem Cells Yue Liu 1, Fei Ye1,9, Kazunari Yamada 1, and reciprocally, two glioblastoma markers, EDN1 and YKL-40 transcripts, were induced. Correspondingly, ... Document Viewer

EXTENSIÓN(DERESECCIÓN(TUMORAL(YMARCADORES(MOLECULARES(EN(EL ...
ExtensiÓn(deresecciÓn(tumoral(ymarcadores(moleculares(en(el(glioblastoma(cerebral:(un(estudio(combinado(de(factores(pronÓsticos(en(una(serie(quirÚrgica(de(105(pacientes gliomas, mgmt y ykl-40 author: mauricio martinez moreno created date: ... Fetch Here

Molecular Properties Of CD133+ glioblastoma Stem Cells ...
Molecular properties of CD133+ glioblastoma stem cells derived the development of YKL-40? infiltrating tumors that dis-play hypervascularity and pseudopalisading necrosis-like features in mouse brain. The molecular profile of purified ... Document Viewer

A COMPARATIVE STUDY OF LAMPs AND YKL-40 TISSUE EXPRESSION IN ...
YKL-40 levels in glioblastoma cell line U87 in condition of hypoxia and ionizing radiation was measured.2 We determined the relationship between the expressions of YKL-40 and LAMPs in glial tumors indicating a possible participation in the processes ... Access Content

Phase I/II Vaccine Study Targeting Novel HLA-A2- Restricted ...
Phase I/II vaccine study targeting novel HLA-A2- YKL-40 and gp100. Methods: The study enrolled twenty-two recurrent malignant glioma patients with glioblastoma (GBM) (n = 13), anaplastic astrocytoma (n = 5), ... Document Viewer

Biomarkers Of glioblastoma Multiforme
Biomarkers of glioblastoma multiforme Stylianos Nicolaidis serum YKL-40 expression, if it correlates with RMI data, provides additional and earlier information and servesasa furtheraidinestablishing theprognosis[13]. ... Read Here

Distinct Transcription Profiles Of Primary And Secondary ...
Distinct Transcription Profiles of Primary and Secondary Glioblastoma Subgroups Cho-Lea Tso,1,2,6 William A. Freije, 1Allen Day, Zugen Chen, (YKL-40) in glioblastoma subgroups. Representative immunohistochemical stainings of YKL-40 in clinical glioblastoma subgroups and normal ... Access Full Source

CHI3L1 - Wikipedia, The Free Encyclopedia
Chitinase-3-like protein 1 (CHI3L1), also known as YKL-40, Targeting YKL-40 with neutralizing antibodies has been proven effective as a treatment in animal models of glioblastoma multiforme. [10] YKL-40 is able to promote angiogenesis through VEGF-dependent and independent pathways. [5] ... Read Article

Glioblastoma In The Elderly: Current And Future Trends
Critical Reviews in Oncology/Hematology 60 (2006) 256–266 Glioblastoma in the elderly: Current and future trends Alba A. Brandesa,∗, Alessia Compostellab, Valeria Blattb, Alicia Tosonib ... Doc Viewer

YKL-40 In HeaLth And Disease: A ChaLLenge For Joint InfLammation
YKL-40 in heaLth and disease: a chaLLenge for joint infLammation Maria Kazakova and Victoria Sarafian activated YKL-40 secretion in glioblastoma cell lines - U87, U118, U373, while fibroblast growth factor (FGF) and TNF-α ... Read Full Source

Current Treatment Options In Adult Glioblastoma
Protein YKL-40.This research is designed to better understand the biology of the protein and translate this into novel determined and patients with glioblastoma can be in class III–VI in order of worsening prognosis. Survival with combined RT/TMZ was higher in RPA class ... Fetch This Document

CURRICULUM VITAE NAME Kenneth Dean Aldape, M.D.
CURRICULUM VITAE NAME Kenneth Dean Aldape, M.D. Present Titles and Affiliation Professor, Pathology/Neuropathology, 5. Mentor, post-doctoral fellowship to K. Bhat. YKL-40 in glioblastoma. American Brain Tumor Foundation. 7/1/05-6/30/07. $70,000 ($35,000/year). 6. ... Fetch Document

Molecular Predictors In Glioblastoma - JAMA Neurology
Molecular Predictors in Glioblastoma Toward Personalized Therapy Howard Colman, MD, PhD; Ken Aldape, MD R ecenttherapeuticadvanceshaveimprovedstandardtreatmentforpatientswithnewly diagnosed glioblastoma. Unfortunately, even with these improvements, only a frac- ... Access Full Source

Molecular Prognostic Factors In glioblastoma: State Of The ...
Glioblastoma multiforme (GBM) is the most frequent and lethal tumor of the CNS, YKL‑40 is produced by GBM cells and released into the serum, where its levels are predictive of an aggressive phenotype and associated with poor overall patient survival. ... Access Full Source

A Review On – Glioblastoma Multiform Naik P.P.*1, Somani R. R.2, Shirodkar P.Y.3, Wagulde S.4, Juvatkar P.5, Kale M.K.6 YKL-40 gene, loss or mutation of PTEN gene, are being investigated. Studies are focusing on new targets such as receptor blockade. ... Fetch Doc

RNA Interference As A Resistance Mechanism Against Crop ...
Regulation of YKL‐40 expression during genotoxic or microenvironmental stress in human glioblastoma cells. Cancer Science. Volume 96, Issue 3, pages 183-190, 16 MAR 2005 DOI: 10.1111/j.1349-7006.2005.00026.x ... Retrieve Full Source

The MET Oncogene Is A Functional Marker Of A glioblastoma ...
3 Introduction Glioblastoma, the highest grade glioma variant, is a relatively rare (yearly incidence of 4-5/100,000 people) but very aggressive tumor, associated with high morbidity, ... Document Viewer

Molecular And Cellular Heterogeneity: The Hallmark Of ...
Of glioblastoma over the last decade has identified several expression of CD40 and CHI3L1/YKL-40. Further work has attempted to develop prognostic assays based on a limited set of genes that correlates with survival, which ... Return Document

YKL-40 Is Differentially Expressed In Human Embryonic Stem ...
YKL-40 Expression by Human Embryonic Stem Cells 5 stained with antibodies against different stem cell markers and differentiation markers to study regional distribution and ... Retrieve Content